发明申请
- 专利标题： Compounds and Methods for Combined Optical-Ultrasound Imaging
- 专利标题（中）： 组合和超声成像方法
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申请号： US11574747申请日： 2005-09-06
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公开(公告)号： US20080077002A1公开(公告)日： 2008-03-27
- 发明人: Tim Nielsen , Steffen Weiss , Tobias Schaeffter , Bernhard Gleich , Paul Haaker , Udo Van Stevendaal , Peter Mazurkewitz
- 申请人： Tim Nielsen , Steffen Weiss , Tobias Schaeffter , Bernhard Gleich , Paul Haaker , Udo Van Stevendaal , Peter Mazurkewitz
- 申请人地址： NL EINDHOVEN
- 专利权人： KONINKLIJKE PHILIPS ELECTRONICS, N.V.
- 当前专利权人： KONINKLIJKE PHILIPS ELECTRONICS, N.V.
- 当前专利权人地址： NL EINDHOVEN
- 优先权： EP04104388.6 20040910
- 国际申请： PCT/IB05/52898 WO 20050906
- 主分类号： A61B5/05
- IPC分类号： A61B5/05
摘要：
The present invention relates to novel methods and compounds for combined opticalultrasound imaging. The compounds of the present invention relate to particles comprising fluorescence donor and acceptor molecules for energy exchange via FRET. The methods of the present invention use ultrasound to modify the distance between donor and acceptor molecules present on the particles, and to consequently modify the fluorescence emitted by the donor and acceptor. The compounds and methods of the present invention are useful in medical or diagnostic imaging.
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