发明申请
- 专利标题： Method for making homozygous genetic modifications
- 专利标题（中）： 纯合遗传修饰方法
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申请号： US11904558申请日： 2007-09-27
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公开(公告)号： US20080078001A1公开(公告)日： 2008-03-27
- 发明人: William Poueymirou , Thomas Dechiara , Wojtek Auerbach , David Frendewey , David Valenzuela
- 申请人： William Poueymirou , Thomas Dechiara , Wojtek Auerbach , David Frendewey , David Valenzuela
- 申请人地址： US NY Tarrytown
- 专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人： Regeneron Pharmaceuticals, Inc.
- 当前专利权人地址： US NY Tarrytown
- 主分类号： C12N15/00
- IPC分类号： C12N15/00
摘要：
Methods of generating modified embryos and mammals by introduction of donor cells into an early stage embryo are provided, such that the resulting embryo and animal generated therefrom has a significant contribution to all tissues from the donor cells and is capable of transmitting the donor cell DNA.
公开/授权文献
- US07659442B2 Method for making homozygous genetic modifications 公开/授权日：2010-02-09
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