发明申请
- 专利标题: Nitrogenous Fused Bicyclic Compound
- 专利标题(中): 含氮双环化合物
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申请号: US11632725申请日: 2005-07-22
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公开(公告)号: US20080081817A1公开(公告)日: 2008-04-03
- 发明人: Iwao Takamuro , Saburo Kawanami , Yasunori Tsuboi , Toshiyuki Himiyama , Yuko Hasegawa , Hideki Mochida , Kouji Nogi
- 申请人: Iwao Takamuro , Saburo Kawanami , Yasunori Tsuboi , Toshiyuki Himiyama , Yuko Hasegawa , Hideki Mochida , Kouji Nogi
- 申请人地址: JP Osaka-shi
- 专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人: Tanabe Seiyaku Co., Ltd.
- 当前专利权人地址: JP Osaka-shi
- 优先权: JP2004-216500 20040723; JP2004-216501 20040723
- 国际申请: PCT/JP05/13459 WO 20050722
- 主分类号: A61K31/497
- IPC分类号: A61K31/497 ; A61K31/519 ; A61P43/00 ; C07D401/00 ; C07D487/00
摘要:
A novel nitrogenous fused bicyclic compound represented by the following general formula [1] or a pharmacologically acceptable salt of the compound. They have excellent SK channel blocking activity and are useful as a medicine. [I] (In the formula, R0 represents hydrogen, halogeno, etc.; R1 represents a group represented by the formula (a) or (b); A represents a group represented by the formula (X) or (Y); D1, D2 and D3 each represents N or CH; R2 represents halogeno or optionally halogenated lower alkyl, etc.; R3 represents hydrogen or lower alkyl; and Q represents lower alkylene.)
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