发明申请
- 专利标题: Stabilizing a nucleic acid for nucleic acid sequencing
- 专利标题(中): 稳定核酸进行核酸测序
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申请号: US11709338申请日: 2007-02-20
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公开(公告)号: US20080085840A1公开(公告)日: 2008-04-10
- 发明人: Philip Buzby
- 申请人: Philip Buzby
- 申请人地址: US MA Cambridge
- 专利权人: Helicos BioSciences Corporation
- 当前专利权人: Helicos BioSciences Corporation
- 当前专利权人地址: US MA Cambridge
- 主分类号: C40B50/18
- IPC分类号: C40B50/18
摘要:
The invention provides methods for sequencing a nucleic acid comprising stabilizing a primer/target nucleic acid duplex on a substrate. Methods of the invention generally contemplate the use of a dual-anchored primer/target nucleic acid duplex, or a stabilizing molecule in a single molecule sequencing reaction.
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