A temperature control system for a container includes a refrigeration circuit having a primary fluid circulating therein and a secondary fluid circuit in communication with a first compartment of the container and a second compartment of the container. The secondary fluid circuit has a secondary fluid separate from the primary fluid circulating therein. The secondary fluid circuit includes a first heat exchange module in communication with an interior load space of the first compartment and a second heat exchange module in communication with an interior load space of the second compartment. Each of the first and second heat exchange modules includes a pump, a heater, a heat exchanger, and a three-way valve. A heat exchange interface between the refrigeration circuit and the secondary fluid circuit is operable to transfer heat from the secondary fluid to the primary fluid.