发明申请
US20080107655A1 HUMAN ANTI-IFN-GAMMA NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-GAMMA PATHWAY INHIBITORS
有权
人类抗IFN-GAMMA作为选择性IFN-GAMMA途径抑制剂中和抗体
- 专利标题: HUMAN ANTI-IFN-GAMMA NEUTRALIZING ANTIBODIES AS SELECTIVE IFN-GAMMA PATHWAY INHIBITORS
- 专利标题(中): 人类抗IFN-GAMMA作为选择性IFN-GAMMA途径抑制剂中和抗体
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申请号: US11962594申请日: 2007-12-21
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公开(公告)号: US20080107655A1公开(公告)日: 2008-05-08
- 发明人: Andrew Welcher , Hilary Chute , Yue-Sheng Li , Haichun Huang
- 申请人: Andrew Welcher , Hilary Chute , Yue-Sheng Li , Haichun Huang
- 申请人地址: US CA Thousand Oaks US NJ Princeton
- 专利权人: Amgen Inc.,Medarex, Inc.
- 当前专利权人: Amgen Inc.,Medarex, Inc.
- 当前专利权人地址: US CA Thousand Oaks US NJ Princeton
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C07K16/18 ; A61P25/00 ; A61P1/00
摘要:
This invention provides antibodies that interact with or bind to human interferon-gamma (IFN-γ) and methods for treating IFN-γ mediated diseases by administering a pharmaceutically effective amount of antibodies to IFN-γ. Methods of detecting the amount of IFN-γ in a sample using antibodies to IFN-γ are also provided.
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