发明申请
US20080125477A1 7-(ACRYLOYL) INDOLE COMPOSITIONS AND METHODS OF MAKING AND USING SAME
审中-公开
7-（丙烯酸）单体组合物及其制备方法和使用方法
- 专利标题： 7-(ACRYLOYL) INDOLE COMPOSITIONS AND METHODS OF MAKING AND USING SAME
- 专利标题（中）： 7-（丙烯酸）单体组合物及其制备方法和使用方法
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申请号： US11748897申请日： 2007-05-15
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公开(公告)号： US20080125477A1公开(公告)日： 2008-05-29
- 发明人: Jasbir Singh , Matt Shaoming Duan , Thorsteinn Thorsteinsson , Mitchell B. Friedman , Mark Gurney
- 申请人： Jasbir Singh , Matt Shaoming Duan , Thorsteinn Thorsteinsson , Mitchell B. Friedman , Mark Gurney
- 申请人地址： IS Reykjavik
- 专利权人： DECODE GENETICS, EHF.
- 当前专利权人： DECODE GENETICS, EHF.
- 当前专利权人地址： IS Reykjavik
- 主分类号： A61K31/404
- IPC分类号： A61K31/404 ; A61P31/00 ; A61P19/00 ; A61P3/00 ; A61P15/00 ; A61P25/00 ; A61P11/00
摘要：
The present invention is directed to pharmaceutical compositions of 7-(acryloyl)indoles, such as 4,5 -Dichloro-thiophene-2-sulfonic acid [(E)-3-[1-(2,4-dichlorophenylmethyl)-5-fluoro-3-methyl-1H-indol-7-yl]-acryloyl]amide (DTSI), having a structure shown below. The invention is also directed to methods of treatment utilizing formulations of the DTSI and processes of preparation of the formulations.
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