发明申请
- 专利标题： Preparation of levalbuterol hydrochloride
- 专利标题（中）： 盐酸左美沙芬醇的制备
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申请号： US12005772申请日： 2007-12-27
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公开(公告)号： US20080132579A1公开(公告)日： 2008-06-05
- 发明人: Valeriano Merli , Silvia Mantovani , Stefano Bianchi , Paola Daverio
- 申请人： Valeriano Merli , Silvia Mantovani , Stefano Bianchi , Paola Daverio
- 专利权人： Teva Pharmaceuticals USA, Inc. for Barbados.
- 当前专利权人： Teva Pharmaceuticals USA, Inc. for Barbados.
- 主分类号： A61K31/137
- IPC分类号： A61K31/137 ; C07C215/20
摘要：
Provided are processes for the preparation of (R)-SLB.D-DBTA salt and levalbuterol hydrochloride. Also provided are levalbuterol hydrochloride degradation products and processes for preparing them. Pharmaceutical compositions comprising at least one levalbuterol hydrochloride of the invention and at least one pharmaceutically-acceptable excipient are also provided.
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