发明申请
US20080138394A1 Composite For Liver-Specific Delivery and Release of Therapeutic Nucleic Acids or Drugs
审中-公开
用于肝脏特异性递送和释放治疗性核酸或药物的复合物
- 专利标题： Composite For Liver-Specific Delivery and Release of Therapeutic Nucleic Acids or Drugs
- 专利标题（中）： 用于肝脏特异性递送和释放治疗性核酸或药物的复合物
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申请号： US11741287申请日： 2007-04-27
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公开(公告)号： US20080138394A1公开(公告)日： 2008-06-12
- 发明人: Meehyein KIM , Soo In Kim , Duckhyang Shin , Mahnhoon Park
- 申请人： Meehyein KIM , Soo In Kim , Duckhyang Shin , Mahnhoon Park
- 申请人地址： KR Yongin-si
- 专利权人： MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人： MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE
- 当前专利权人地址： KR Yongin-si
- 优先权： KR10-2006-0110402 20061109
- 主分类号： A61K9/127
- IPC分类号： A61K9/127 ; A61K31/7088
摘要：
The inventive composite having a nanoscale particle size can specifically deliver therapeutic nucleic acids or drugs to the liver and selectively release them into hepatic cells to manifest potent therapeutic effects without inducing any enzymatic abnormalities or pathological damage to the normal liver function, when administered together with the therapeutic agents.