发明申请
- 专利标题： MODULATION OF FORKHEAD BOX O1A EXPRESSION
- 专利标题（中）： FORKHEAD BOX O1A表达式的调制
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申请号： US11739017申请日： 2007-04-23
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公开(公告)号： US20080153767A1公开(公告)日： 2008-06-26
- 发明人: Kenneth W. Dobie , Sanjay Bhanot , Murielle Veniant-Ellison , Richard A. Lindberg , John R. Shutter , Robert McKay , Sanjay K. Pandey
- 申请人： Kenneth W. Dobie , Sanjay Bhanot , Murielle Veniant-Ellison , Richard A. Lindberg , John R. Shutter , Robert McKay , Sanjay K. Pandey
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07H21/04 ; C12Q1/68 ; C12N5/02
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of forkhead box O1A. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding forkhead box O1A. Methods of using these compounds for modulation of forkhead box O1A expression and for treatment of diseases associated with expression of forkhead box O1A are provided, in particular, for methods of treating diabetes.
公开/授权文献
- US07807649B2 Modulation of forkhead box O1A expression 公开/授权日：2010-10-05
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