发明申请
- 专利标题： DETERMINATION OF HISTAMINE-3 BIOACTIVITY
- 专利标题（中）： 组胺3生物活性的测定
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申请号： US11950560申请日： 2007-12-05
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公开(公告)号： US20080159958A1公开(公告)日： 2008-07-03
- 发明人: Richard J. Radek , R. Scott Bitner , Marlon D. Cowart , Jorge D. Brioni , Timothy A. Esbenshade
- 申请人： Richard J. Radek , R. Scott Bitner , Marlon D. Cowart , Jorge D. Brioni , Timothy A. Esbenshade
- 申请人地址： US IL Abbott Park
- 专利权人： Abbott Laboratories
- 当前专利权人： Abbott Laboratories
- 当前专利权人地址： US IL Abbott Park
- 主分类号： A61K49/00
- IPC分类号： A61K49/00
摘要：
The invention relates to an in vivo method for determining the bioactivity of chemical compounds as histamine-3 receptor (H3R) ligands, and provides animal models to determine such bioactivity. The invention further relates to methods for screening therapeutic compounds demonstrating a desired property, using such methods and models described.
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