发明申请
US20080163386A1 CRBs as Modifiers of Branching Morphogenesis and Methods of Use
审中-公开
CRB作为分支形态发生的修饰剂和使用方法
- 专利标题： CRBs as Modifiers of Branching Morphogenesis and Methods of Use
- 专利标题（中）： CRB作为分支形态发生的修饰剂和使用方法
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申请号： US11627977申请日： 2007-01-28
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公开(公告)号： US20080163386A1公开(公告)日： 2008-07-03
- 发明人: Felix D. Karim , Linda Nolan Keyes , Gregory D. Plowman , Michael Martin Ollmann , Mark E. Maxwell , Thierry Tidiane Diagana
- 申请人： Felix D. Karim , Linda Nolan Keyes , Gregory D. Plowman , Michael Martin Ollmann , Mark E. Maxwell , Thierry Tidiane Diagana
- 申请人地址： US CA South San Francisco
- 专利权人： EXELIXIS, INC.
- 当前专利权人： EXELIXIS, INC.
- 当前专利权人地址： US CA South San Francisco
- 主分类号： G01N33/483
- IPC分类号： G01N33/483 ; G01N33/50 ; C12N5/06 ; C12Q1/02
摘要：
Human CRB genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of CRB are provided.
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