发明申请
US20080176842A1 BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS
审中-公开
BIS-磺酰胺羟丙基氨基转移酶抑制剂
- 专利标题: BIS-SULFONAMIDE HYDROXYETHYLAMINO RETROVIRAL PROTEASE INHIBITORS
- 专利标题(中): BIS-磺酰胺羟丙基氨基转移酶抑制剂
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申请号: US11940035申请日: 2007-11-14
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公开(公告)号: US20080176842A1公开(公告)日: 2008-07-24
- 发明人: John N. Freskos , Daniel P. Getman , John J. Talley , James A. Sikorski
- 申请人: John N. Freskos , Daniel P. Getman , John J. Talley , James A. Sikorski
- 申请人地址: US NY New York
- 专利权人: G.D. SEARLE LLC
- 当前专利权人: G.D. SEARLE LLC
- 当前专利权人地址: US NY New York
- 主分类号: A61K31/18
- IPC分类号: A61K31/18 ; A61K31/495 ; A61K31/445 ; A61K31/496 ; A61K31/5377 ; C07D413/02 ; C07D401/02 ; C07D403/02 ; C07D295/14 ; C07C311/00 ; A61P31/18
摘要:
Bis-sulfonamido hydroxyethylamino compounds are effective as retroviral protease inhibitors, and in particular as inhibitors of HIV protease. The present invention relates to retroviral protease inhibiting compounds of the formula: or a pharmaceutically acceptable salt, prodrug or ester thereof, wherein the variables are as defined herein.
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