发明申请
US20080176964A1 AGENTS WHICH REGULATE, INHIBIT, OR MODULATE THE ACTIVITY AND/OR EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) AS A UNIQUE MEANS TO BOTH LOWER INTRAOCULAR PRESSURE AND TREAT GLAUCOMATOUS RETINOPATHIES/OPTIC NEUROPATHIES
审中-公开
代理，禁止或调节连接性组织生长因子（CTGF）的活动和/或表达，作为双重下降的压力和治疗玻璃体积反射/视神经病变的独特手段
- 专利标题： AGENTS WHICH REGULATE, INHIBIT, OR MODULATE THE ACTIVITY AND/OR EXPRESSION OF CONNECTIVE TISSUE GROWTH FACTOR (CTGF) AS A UNIQUE MEANS TO BOTH LOWER INTRAOCULAR PRESSURE AND TREAT GLAUCOMATOUS RETINOPATHIES/OPTIC NEUROPATHIES
- 专利标题（中）： 代理，禁止或调节连接性组织生长因子（CTGF）的活动和/或表达，作为双重下降的压力和治疗玻璃体积反射/视神经病变的独特手段
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申请号： US12024821申请日： 2008-02-01
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公开(公告)号： US20080176964A1公开(公告)日： 2008-07-24
- 发明人: Debra L. Fleenor , Allan Shepard , Nasreen Jacobson , Iok-Hou Pang , Abbot F. Clark
- 申请人： Debra L. Fleenor , Allan Shepard , Nasreen Jacobson , Iok-Hou Pang , Abbot F. Clark
- 申请人地址： US TX Fort Worth
- 专利权人： ALCON RESEARCH, LTD.
- 当前专利权人： ALCON RESEARCH, LTD.
- 当前专利权人地址： US TX Fort Worth
- 主分类号： A61K45/00
- IPC分类号： A61K45/00 ; A61P27/02
摘要：
The present invention provides a method for lowering intraocular pressure and providing neuroprotection to a patient in need thereof by administering a therapeutically effective amount of at least one non-nucleotide or non-protein agent that inhibits expression and/or signaling of connective tissue growth factor (CTGF).