发明申请
- 专利标题： 4-Amino-5-Cyanopyrimidine Derivatives
- 专利标题（中）： 4-氨基-5-氰基嘧啶衍生物
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申请号： US11579067申请日： 2005-04-28
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公开(公告)号： US20080182854A1公开(公告)日： 2008-07-31
- 发明人: Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
- 申请人： Masaya Kato , Norifumi Sato , Minoru Okada , Tetsuyuki Uno , Nobuaki Ito , Yasuhiro Takeji , Hisashi Shinohara , Masahiro Fuwa
- 申请人地址： JP Tokyo
- 专利权人： OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人： OTSUKA PHARMACEUTICAL CO., LTD.
- 当前专利权人地址： JP Tokyo
- 优先权： JP2004-135999 20040430
- 国际申请： PCT/JP05/08568 WO 20050428
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; C07D401/12 ; C07D401/14 ; A61P27/06 ; A61P27/02
摘要：
The present invention provides 4-amino-5-cyanopyrimidine derivatives of the formula: wherein R1, R2 and R3 are defined herein, or pharmaceutically acceptable salts thereof, having a safe and potent adenosine A2a receptor agonistic activity; and also provides an adenosine A2a receptor agonist, an intraocular pressure reducing agent, or a medicine for treating glaucoma, etc., which comprises the compound as an active ingredient.
公开/授权文献
- US07834002B2 4-amino-5-cyanopyrimidine derivatives 公开/授权日：2010-11-16
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