- 专利标题： HCV RNA-dependent RNA polymerase
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申请号： US12002392申请日： 2007-12-17
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公开(公告)号： US20080187903A1公开(公告)日： 2008-08-07
- 发明人: Donald J. Graham , Amy L. Simcoe , Steven W. Ludmerer , Osvaldo A. Flores , Robert L. LaFemina
- 申请人： Donald J. Graham , Amy L. Simcoe , Steven W. Ludmerer , Osvaldo A. Flores , Robert L. LaFemina
- 主分类号： C12Q1/00
- IPC分类号： C12Q1/00 ; C07K14/005 ; C07H21/04 ; C12N15/63
摘要：
The present invention features NS5B polypeptides from different clinically important HCV genotypes. The polypeptides can be used individually, or as part of a panel of RNA-dependent RNA polymerases, to evaluate the effectiveness of a compound to inhibit NS5B activity.
公开/授权文献
- US07569374B2 HCV RNA-dependent RNA polymerase 公开/授权日：2009-08-04