发明申请
- 专利标题: Radioactive Diagnostic Imaging Agent
- 专利标题(中): 放射诊断成像剂
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申请号: US11921139申请日: 2006-06-08
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公开(公告)号: US20080193379A1公开(公告)日: 2008-08-14
- 发明人: Takayuki Shimada , Akira Nakatani , Keietsu Takahashi
- 申请人: Takayuki Shimada , Akira Nakatani , Keietsu Takahashi
- 申请人地址: JP Tokyo
- 专利权人: Nihon Medi-Physics Co., Ltd.
- 当前专利权人: Nihon Medi-Physics Co., Ltd.
- 当前专利权人地址: JP Tokyo
- 优先权: JP2005-173800 20050614
- 国际申请: PCT/JP2006/311513 WO 20060608
- 主分类号: A61K51/04
- IPC分类号: A61K51/04
摘要:
It is intended to provide a radioactive diagnostic imaging agent comprising a radioactive halogen-labeled compound as an active ingredient, in which the active ingredient is prevented from radiolysis and its stability is improved. This is achieved by adding a biologically-acceptable sugar or sugar alcohol to the radioactive diagnostic imaging agent in an amount effective to prevent radiolysis. The amount of the sugar or sugar alcohol to be added is preferably 10 (mmol/L)/GBq/mL or more, and more preferably 50 (mmol/L)/GBq/mL or more. The sugar is preferably selected from the group consisting of erythrose, threose, ribose, arabinose, xylose, lyxose, allose, altrose, glucose, mannose, gulose, idose, galactose, talose, erythrulose, ribulose, xylulose, psicose, fructose, sorbose, and tagatose. The sugar alcohol is preferably selected from the group consisting of erythritol, xylitol, sorbitol, and mannitol.
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