发明申请
- 专利标题： Tissue Repair Using Allogenic Dermal Fibroblasts
- 专利标题（中）： 使用同种异体皮肤成纤维细胞的组织修复
-
申请号： US11915514申请日： 2006-05-25
-
公开(公告)号： US20080199440A1公开(公告)日： 2008-08-21
- 发明人: Mike Leek , Paul Kemp
- 申请人： Mike Leek , Paul Kemp
- 优先权： GB0510714.9 20050526; GB0521491.1 20051021
- 国际申请： PCT/GB2006/001916 WO 20060525
- 主分类号： A61K35/12
- IPC分类号： A61K35/12 ; C12N5/06 ; A61P19/00
摘要：
The present invention provides a method for the repair of subcutaneous or dermal tissue in a subject, comprising in one aspect the injection of a suspension of allogeneic dermal fibroblasts into the subject. By injecting a suspension of allogeneic cells, the invention provides, for example, long-term augmentation of the subadjacent tissue without the disadvantages that accompany the preparation and/or use of presently available materials such as autologous fibroblasts cells or collagen. According to a first aspect of the invention there is provided a method for the augmentation of subcutaneous or dermal tissue in a subject, which method comprises the steps of: (i) providing a suspension of allogeneic dermal fibroblasts; and (ii) injecting an effective volume of the suspension into tissue subadjacent to the subcutaneous or dermal tissue so that the tissue is augmented. The method is preferably cosmetic.