发明申请
- 专利标题： FEN Endonucleases
- 专利标题（中）： FEN内切核酸酶
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申请号： US11926006申请日： 2007-10-28
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公开(公告)号： US20080199936A1公开(公告)日： 2008-08-21
- 发明人: Victor I. Lyamichev , Michael W. Kaiser , Natasha Lyamicheva
- 申请人： Victor I. Lyamichev , Michael W. Kaiser , Natasha Lyamicheva
- 申请人地址： US WI Madison
- 专利权人： THIRD WAVE TECHNOLOGIES, INC.
- 当前专利权人： THIRD WAVE TECHNOLOGIES, INC.
- 当前专利权人地址： US WI Madison
- 主分类号： C12N9/00
- IPC分类号： C12N9/00
摘要：
The present invention provides novel cleavage agents and polymerases for the cleavage and modification of nucleic acid. The cleavage agents and polymerases find use, for example, for the detection and characterization of nucleic acid sequences and variations in nucleic acid sequences. In some embodiments, the 5′ nuclease activity of a variety of enzymes is used to cleave a target-dependent cleavage structure, thereby indicating the presence of specific nucleic acid sequences or specific variations thereof.
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