发明申请
- 专利标题: Compounds Effecting Glucokinase
- 专利标题(中): 影响葡萄糖激酶的化合物
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申请号: US12024561申请日: 2008-02-01
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公开(公告)号: US20080207636A1公开(公告)日: 2008-08-28
- 发明人: Scott Boyd , Peter William Rodney Caulkett , Rodney Brian Hargreaves , Suzanne Saxon Bowker , Roger James , Clifford David Jones , Darren McKerrecher , Michael Howard Block , Craig Johnstone
- 申请人: Scott Boyd , Peter William Rodney Caulkett , Rodney Brian Hargreaves , Suzanne Saxon Bowker , Roger James , Clifford David Jones , Darren McKerrecher , Michael Howard Block , Craig Johnstone
- 申请人地址: SE Sodertalje
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: SE Sodertalje
- 优先权: SE0102764-8 20010817
- 主分类号: A61K31/496
- IPC分类号: A61K31/496 ; C07D277/20 ; A61K31/426 ; A61K31/433 ; A61P3/10 ; A61K31/4436 ; A61K31/415 ; C07D231/10 ; C07D213/02 ; A61P3/04 ; C07D285/12 ; C07D295/00
摘要:
The invention relates to the use of a compound of Formula (I) or a salt, solvate or prodrug thereof, wherein R1, R2, R3, n and m are as described in the specification, in the preparation of a medicament for the treatment or prevention of a disease condition mediated through glucokinase (GLK), such as type 2 diabetes. The invention also relates to a novel group of compounds of Formula (I) and to methods for preparing compounds of Formula (I).
公开/授权文献
- US07524957B2 Compounds effecting glucokinase 公开/授权日:2009-04-28