A method of reproducing information from an optical disc, and an optical disc reproducing apparatus using the method, including reproducing information from an optical disc having a plurality of regions with differing physical specifications, the information is read using optical beams having differing spot sizes in regions of the optical disc having differing physical specifications. The method enables the optical disc having the regions with differing physical specifications to stably reproduce information from all regions of the optical disc by minimizing regional reproduction performance differences caused in the reproduction process.