发明申请
- 专利标题： Targeting complement factor H for treatment of diseases
- 专利标题（中）： 靶向补体因子H用于治疗疾病
-
申请号： US11821370申请日： 2007-06-21
-
公开(公告)号： US20080221011A1公开(公告)日： 2008-09-11
- 发明人: Gary Gilkeson , Stephen Tomlinson , V. Michael Holers , Baerbel Rohrer
- 申请人： Gary Gilkeson , Stephen Tomlinson , V. Michael Holers , Baerbel Rohrer
- 主分类号： A61K38/02
- IPC分类号： A61K38/02 ; C07K2/00 ; C07K19/00 ; C07H21/04 ; C12N15/63 ; C12N5/06
摘要：
The invention provides a CR2-FH molecule comprising a CR2 portion comprising CR2 protein or a fragment thereof and a FH portion comprising a factor H protein or a fragment thereof, and pharmaceutical compositions comprising a CR2-FH molecule. Also provided are methods of using the compositions for treatment diseases in which the alternative complement pathway is implicated, such as age-related macular degeneration, rheumatoid arthritis, and ischemia reperfusion.
公开/授权文献
- US07759304B2 Targeting complement factor H for treatment of diseases 公开/授权日：2010-07-20
信息查询
IPC分类:
