发明申请
- 专利标题: Cyclic Peptide Isolation by Spray Drying
- 专利标题(中): 循环肽通过喷雾干燥分离
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申请号: US12064896申请日: 2006-08-29
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公开(公告)号: US20080227693A1公开(公告)日: 2008-09-18
- 发明人: Rowena Fernandez Choudrie , Kaushik J. Dave , Steven R. Johnson
- 申请人: Rowena Fernandez Choudrie , Kaushik J. Dave , Steven R. Johnson
- 申请人地址: US NJ Cranbury
- 专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人: PALATIN TECHNOLOGIES, INC.
- 当前专利权人地址: US NJ Cranbury
- 国际申请: PCT/US06/33465 WO 20060829
- 主分类号: A61K38/12
- IPC分类号: A61K38/12 ; C07K1/14 ; C07K7/64
摘要:
Methods for isolation of a synthetic cyclic peptide by spray drying, including spray drying at elevated temperatures, products made by the methods, and synthetic cyclic peptides preparations with defined characteristics, including an essentially amorphous acid addition salt of Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH in the form of a fine powder with a particle diameter of about 2 to about 20 microns.
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