专利检索 ap:("Rowena Fernandez Choudrie" OR "Kaushik J. Dave" OR "Steven R. Johnson") AND inv:"Rowena Fernandez Choudrie" 第 1 页

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发明申请
Cyclic Peptide Isolation by Spray Drying 审中-公开
标题翻译：循环肽通过喷雾干燥分离

公开(公告)号：US20080227693A1

公开(公告)日：2008-09-18

申请号：US12064896

申请日：2006-08-29

申请人： Rowena Fernandez Choudrie , Kaushik J. Dave , Steven R. Johnson

发明人： Rowena Fernandez Choudrie , Kaushik J. Dave , Steven R. Johnson

IPC分类号： A61K38/12 , C07K1/14 , C07K7/64

CPC分类号： C07K7/56 , C07K1/14

摘要： Methods for isolation of a synthetic cyclic peptide by spray drying, including spray drying at elevated temperatures, products made by the methods, and synthetic cyclic peptides preparations with defined characteristics, including an essentially amorphous acid addition salt of Ac-Nle-cyclo(-Asp-His-D-Phe-Arg-Trp-Lys)-OH in the form of a fine powder with a particle diameter of about 2 to about 20 microns.

摘要翻译： 通过喷雾干燥分离合成环肽的方法，包括在高温下的喷雾干燥，通过该方法制备的产物和具有确定特征的合成环肽制剂，包括Ac-Nle-cyclo（-Asp）的基本无定形酸加成盐 -His-D-Phe-Arg-Trp-Lys）-OH，其粒径为约2至约20微米。