发明申请
US20080227834A1 DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS
有权
2-氨基苯甲酸和2-氨基氧杂环丁烷的衍生物，其制备方法及其作为药物组合物的用途
- 专利标题： DERIVATIVES OF 2-AMINOTHIAZOLES AND 2-AMINO-OXAZOLES, PROCESSES FOR THEIR PREPARATION AND THEIR USE AS PHARMACEUTICAL COMPOSITIONS
- 专利标题（中）： 2-氨基苯甲酸和2-氨基氧杂环丁烷的衍生物，其制备方法及其作为药物组合物的用途
-
申请号： US12055771申请日： 2008-03-26
-
公开(公告)号： US20080227834A1公开(公告)日： 2008-09-18
- 发明人: Stefanie Keil , Matthias Urmann , Maike Glien , Wolfgang Wendler , Karen Chandross , Lan Lee
- 申请人： Stefanie Keil , Matthias Urmann , Maike Glien , Wolfgang Wendler , Karen Chandross , Lan Lee
- 申请人地址： FR Paris
- 专利权人： SANOFI-AVENTIS
- 当前专利权人： SANOFI-AVENTIS
- 当前专利权人地址： FR Paris
- 优先权： EP05021279.4 20050929
- 主分类号： A61K31/4245
- IPC分类号： A61K31/4245 ; C07D271/07 ; A61P3/00
摘要：
The present invention relates to derivatives of 2-aminothiazoles and 2-aminooxazoles in all its stereoisomeric forms, enantiomeric forms and mixtures in any ratio, and its physiologically acceptable salts and tautomeric forms showing peroxisome proliferators activator receptor (PPAR) delta agonist activity. These compounds are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.
公开/授权文献
信息查询
