发明申请
- 专利标题： Peptidase Inhibitors
- 专利标题（中）： 肽酶抑制剂
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申请号： US11571857申请日： 2005-07-21
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公开(公告)号： US20080234292A1公开(公告)日： 2008-09-25
- 发明人: Susan Marie Royalty , James Ford Burns , Jan Jozef Scicinski , Gunnar Erik Jagdmann, Jr. , Robert James Foglesong , Kellee Griffin Ring , Tatyana Dyakonov , David Middlemiss
- 申请人： Susan Marie Royalty , James Ford Burns , Jan Jozef Scicinski , Gunnar Erik Jagdmann, Jr. , Robert James Foglesong , Kellee Griffin Ring , Tatyana Dyakonov , David Middlemiss
- 国际申请： PCT/US2005/025837 WO 20050721
- 主分类号： A61K31/40
- IPC分类号： A61K31/40 ; C07D207/16 ; C07D401/12 ; C07D403/12 ; C07D413/12 ; C07D277/04 ; A61K31/497 ; A61K31/506 ; A61K31/4439 ; A61K31/426 ; A61K31/422 ; A61P3/10
摘要：
The present invention relates to a series of novel compounds having the formula (I) wherein: X is NR3 or O; n is 1 or 2; A is a bicyclic carbocycle and R1 and R2 are as described herein. The compounds are useful as DPP-IV inhibitors, such as for the treatment of diabetes.
公开/授权文献
- US07842707B2 Peptidase inhibitors 公开/授权日：2010-11-30