Invention Application
- Patent Title: PYRROLE DERIVATIVES AS ANTIMYCOBACTERIAL COMPOUNDS
- Patent Title (中): 吡咯衍生物作为抗微生物化合物
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Application No.: US12137170Application Date: 2008-06-11
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Publication No.: US20080242676A1Publication Date: 2008-10-02
- Inventor: Sudershan Kumar Arora , Neelima Sinha , Sanjay Jain , Ram Shankar Upadhayaya , Gourhari Jana , Shankar Ajay , Rakesh Kumar Sinha
- Applicant: Sudershan Kumar Arora , Neelima Sinha , Sanjay Jain , Ram Shankar Upadhayaya , Gourhari Jana , Shankar Ajay , Rakesh Kumar Sinha
- Applicant Address: IN Mumbai
- Assignee: Lupin Limited
- Current Assignee: Lupin Limited
- Current Assignee Address: IN Mumbai
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D403/02 ; C12N1/00 ; C12N1/20 ; A61P31/04

Abstract:
Novel pyrrole derivatives of formula (I) and their pharmaceutically acceptable acid addition salts having superior antimycobacterial activity against clinically sensitive as well as resistant strains of Mycobacterium tuberculosis as well as having lesser toxicity compared to known compounds. The use of the novel compounds of formula (I) for treatment of latent tuberculosis including Multi Drug Resistant Tuberculosis (MDR TB). The methods for preparation of the novel compounds, pharmaceutical compositions containing the novel compounds and method of treating MDR TB by administration of compounds of formula (I).
Public/Granted literature
- US07763602B2 Pyrrole derivatives as antimycobacterial compounds Public/Granted day:2010-07-27
Information query
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