发明申请
- 专利标题： THIAZOLIDINEDIONE DERIVATIVES AS PI3 KINASE INHIBITORS
- 专利标题（中）： 噻唑烷二酮衍生物作为PI3激酶抑制剂
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申请号： US11844404申请日： 2007-08-24
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公开(公告)号： US20080255115A1公开(公告)日： 2008-10-16
- 发明人: Michael Gerard Darcy , Steven David Knight , Nicholas D. Adams , Stanley J. Schmidt
- 申请人： Michael Gerard Darcy , Steven David Knight , Nicholas D. Adams , Stanley J. Schmidt
- 优先权： USPCT/US07/66359 20070411
- 主分类号： C07D401/14
- IPC分类号： C07D401/14 ; A61K31/4709 ; A61K31/497 ; A61K31/501 ; C07D413/14 ; A61K31/5377 ; A61P35/00
摘要：
Invented is a method of inhibiting the activity/function of PI3 kinases using thiazolidinedione derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of thiazolidinedione derivatives.
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