发明申请
- 专利标题: MAPK/ERK KINASE INHIBITORS
- 专利标题(中): MAPK / ERK激酶抑制剂
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申请号: US11958999申请日: 2007-12-18
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公开(公告)号: US20080255160A1公开(公告)日: 2008-10-16
- 发明人: Qing Dong , Xianchang Gong , Stephen W. Kaldor , Toufike Kanouni , Nicholas Scorah , Michael B. Wallace , Feng Zhou
- 申请人: Qing Dong , Xianchang Gong , Stephen W. Kaldor , Toufike Kanouni , Nicholas Scorah , Michael B. Wallace , Feng Zhou
- 主分类号: A61K31/519
- IPC分类号: A61K31/519 ; C07D487/02 ; C12N9/99 ; A61P35/00 ; A61P9/10 ; A61P11/06 ; A61P13/12 ; A61P17/00
摘要:
Compounds of the following formula are provided for use with MEK: wherein the variables are as defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds; methods and intermediates useful for making the compounds; and methods of using said compounds.
公开/授权文献
- US08030317B2 MAPK/ERK kinase inhibitors 公开/授权日:2011-10-04