发明申请
US20080260838A1 GLUCAGON-LIKE PEPTIDE 1 (GLP-1) PHARMACEUTICAL FORMULATIONS
审中-公开
GLUCAGON-LIKE PEPTIDE 1(GLP-1)PHARMACEUTICAL FORMULATIONS
- 专利标题: GLUCAGON-LIKE PEPTIDE 1 (GLP-1) PHARMACEUTICAL FORMULATIONS
- 专利标题(中): GLUCAGON-LIKE PEPTIDE 1(GLP-1)PHARMACEUTICAL FORMULATIONS
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申请号: US11735957申请日: 2007-04-16
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公开(公告)号: US20080260838A1公开(公告)日: 2008-10-23
- 发明人: Mark J. Hokenson , David Brandt , Mark King , Stephanie Greene , Mary Faris , Keith Oberg , Wayman Wendell Cheatham , Cohava Gelber , Andrea Leone-Bay
- 申请人: Mark J. Hokenson , David Brandt , Mark King , Stephanie Greene , Mary Faris , Keith Oberg , Wayman Wendell Cheatham , Cohava Gelber , Andrea Leone-Bay
- 申请人地址: US CA Valencia
- 专利权人: MANNKIND CORPORATION
- 当前专利权人: MANNKIND CORPORATION
- 当前专利权人地址: US CA Valencia
- 主分类号: A61K9/14
- IPC分类号: A61K9/14 ; A61K38/16 ; A61P3/10 ; A61P3/04 ; A61P35/00
摘要:
A composition is disclosed comprising glucagon-like peptide 1 (GLP-1) particles in combination with diketopiperazine (DKP) that is stable both in vitro and in vivo. The composition has utility as a pharmaceutical formulation for treating diseases such as diabetes, cancers, and obesity but is not limited to such diseases or conditions. In particularly, the composition has utility as a pharmaceutical formulation for pulmonary delivery.
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