发明申请
US20080262228A1 Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof
审中-公开
5-氟-8-喹啉代谢物及其制备方法及用途
- 专利标题： Metabolites of 5-fluoro-8- quinoline and methods of preparation and uses thereof
- 专利标题（中）： 5-氟-8-喹啉代谢物及其制备方法及用途
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申请号： US11986895申请日： 2007-11-27
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公开(公告)号： US20080262228A1公开(公告)日： 2008-10-23
- 发明人: Jianyao Wang , Alana Upthagrove , Lin Deng , Wayne Everett Childers , Zhongqi Shen , William Demaio , Robin D. Moore , Zeen Tong , Li Shen , Pixu Li , Michael K. May
- 申请人： Jianyao Wang , Alana Upthagrove , Lin Deng , Wayne Everett Childers , Zhongqi Shen , William Demaio , Robin D. Moore , Zeen Tong , Li Shen , Pixu Li , Michael K. May
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D401/14 ; A61P25/00
摘要：
The present invention relates to novel metabolites of 5-Fluoro-8-{4-[4-(6-methoxyquinolin-8-yl)piperazin-1-yl]piperidin-1-yl}quinoline, which can be useful in treating CNS disorders. The present invention further relates to processes for their preparation, to pharmaceutical compositions comprising them, and to methods of using them.