发明申请
- 专利标题: Pik4ca As Modifier of the Rac Pathway and Methods of Use
- 专利标题(中): Pik4ca作为Rac通路的修改者和使用方法
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申请号: US11575233申请日: 2005-09-15
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公开(公告)号: US20080263684A1公开(公告)日: 2008-10-23
- 发明人: Lisa C. Kadyk , George Ross Francis , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人: Lisa C. Kadyk , George Ross Francis , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人地址: US CA South San Francisco
- 专利权人: EXELIXIS INC.
- 当前专利权人: EXELIXIS INC.
- 当前专利权人地址: US CA South San Francisco
- 国际申请: PCT/US05/32838 WO 20050915
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; G01N33/53 ; C12Q1/02 ; C12Q1/48 ; G01N33/00
摘要:
Human PIK4CA genes are identified as modulators of the RAC pathway, and thus are therapeutic targets for disorders associated with defective RAC function. Methods for identifying modulators of RAC, comprising screening for agents that modulate the activity of PIK4CA are provided.
公开/授权文献
- US08481269B2 PIK4CA as modifier of the Rac pathway and methods of use 公开/授权日:2013-07-09
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