发明申请
US20080269269A1 Crystalline Forms of 4-Methyl-N- [3-(4-Methyl-Imidazol-1-Yl)-5-Trifluoromethyl-Phenyl]-3- (4-Pyridin-3-Yl-Pyrimidin-2-Ylamino) -Benzamide
有权
4-甲基-N- [3-(4-甲基 - 咪唑-1-基)-5-三氟甲基 - 苯基] -3-(4-吡啶-3-基] - 嘧啶-2-基]氨基) - 苯甲酰胺的结晶形式
- 专利标题: Crystalline Forms of 4-Methyl-N- [3-(4-Methyl-Imidazol-1-Yl)-5-Trifluoromethyl-Phenyl]-3- (4-Pyridin-3-Yl-Pyrimidin-2-Ylamino) -Benzamide
- 专利标题(中): 4-甲基-N- [3-(4-甲基 - 咪唑-1-基)-5-三氟甲基 - 苯基] -3-(4-吡啶-3-基] - 嘧啶-2-基]氨基) - 苯甲酰胺的结晶形式
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申请号: US11995906申请日: 2006-07-18
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公开(公告)号: US20080269269A1公开(公告)日: 2008-10-30
- 发明人: Paul W. Manley , Wen-Chung Shieh , Paul Allen Sutton , Piotr H. Karpinski , Raeann Wu , Stephanie Monnier , Jorg Brozio
- 申请人: Paul W. Manley , Wen-Chung Shieh , Paul Allen Sutton , Piotr H. Karpinski , Raeann Wu , Stephanie Monnier , Jorg Brozio
- 国际申请: PCT/US06/27875 WO 20060718
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; C07D401/14
摘要:
Polymorphic forms of 4-methyl-N-[3-(4-methyl-imidazol-1-yl)-5-trifluoromethyl-phenyl]-3-(4-pyridin-3-yl-pyrimidin-2-ylamino)-benzamide free base and salts thereof are prepared by various processes.
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