发明申请
US20080269322A1 Substituted Aminophenylsulfonamide Compounds as Hiv Protease Inhibitor
有权
取代的氨基苯磺酰胺化合物作为Hiv蛋白酶抑制剂
- 专利标题： Substituted Aminophenylsulfonamide Compounds as Hiv Protease Inhibitor
- 专利标题（中）： 取代的氨基苯磺酰胺化合物作为Hiv蛋白酶抑制剂
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申请号： US12094799申请日： 2006-11-28
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公开(公告)号： US20080269322A1公开(公告)日： 2008-10-30
- 发明人: Herman Augustinus De Kock , Tim Hugo Maria Jonckers , Stefaan Julien Last , Paul Jozef Gabriel Maria Boonants , Dominique Louis Nestor Ghislain Surleraux , Piet Tom Bert Paul Wigerinck
- 申请人： Herman Augustinus De Kock , Tim Hugo Maria Jonckers , Stefaan Julien Last , Paul Jozef Gabriel Maria Boonants , Dominique Louis Nestor Ghislain Surleraux , Piet Tom Bert Paul Wigerinck
- 优先权： EP05111394.2 20051128
- 国际申请： PCT/EP06/68993 WO 20061128
- 主分类号： A61K31/34
- IPC分类号： A61K31/34 ; C07D493/04
摘要：
The present invention concerns substituted aminophenylsulfonamide compounds, their use as protease inhibitors, in particular as broad-spectrum HIV protease inhibitors, processes for their preparation as well as pharmaceutical compositions and diagnostic kits comprising them. The present invention also concerns combinations of the present substituted aminophenylsulfonamide compounds with another anti-retroviral agent. It further relates to their use in assays as reference compounds or as reagents.
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