发明申请
US20080274049A1 Cytotoxicity mediation of cells evidencing surface expression of CD44
有权
证实CD44表面表达的细胞的细胞毒性调解
- 专利标题： Cytotoxicity mediation of cells evidencing surface expression of CD44
- 专利标题（中）： 证实CD44表面表达的细胞的细胞毒性调解
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申请号： US12217279申请日： 2008-07-01
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公开(公告)号： US20080274049A1公开(公告)日： 2008-11-06
- 发明人: David S. F. Young , Helen P. Findlay , Susan E. Hahn , Lisa M. Cechetto , Fortunata McConkey
- 申请人： David S. F. Young , Helen P. Findlay , Susan E. Hahn , Lisa M. Cechetto , Fortunata McConkey
- 专利权人： Arius Research Inc.
- 当前专利权人： Arius Research Inc.
- 主分类号： A61K51/10
- IPC分类号： A61K51/10 ; C12N5/08 ; A61K39/395 ; G01N33/574 ; A61P35/00 ; C07K16/28 ; A61K39/44
摘要：
This invention relates to the diagnosis and treatment of cancerous diseases, particularly to the mediation of cytotoxicity of tumor cells; and most particularly to the use of cancerous disease modifying antibodies (CDMAB), optionally in combination with one or more chemotherapeutic agents, as a means for initiating the cytotoxic response. The invention further relates to binding assays which utilize the CDMAB of the instant invention.
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