发明申请
US20080274122A1 Plks as Modifiers of the Beta Catenin Pathway and Methods of Use
失效
作为β-联蛋白途径和使用方法的修饰物
- 专利标题: Plks as Modifiers of the Beta Catenin Pathway and Methods of Use
- 专利标题(中): 作为β-联蛋白途径和使用方法的修饰物
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申请号: US10580131申请日: 2004-11-23
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公开(公告)号: US20080274122A1公开(公告)日: 2008-11-06
- 发明人: Helen Francis-Lang , Christopher G. Winter , Richard Benn Abegania Ventura , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人: Helen Francis-Lang , Christopher G. Winter , Richard Benn Abegania Ventura , Lynn Margaret Bjerke , Timothy S. Heuer
- 申请人地址: US CA South San Francisco
- 专利权人: EXELIXIS, INC.
- 当前专利权人: EXELIXIS, INC.
- 当前专利权人地址: US CA South San Francisco
- 国际申请: PCT/US2004/039549 WO 20041123
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; C12Q1/68 ; C12Q1/02 ; A61K31/70 ; A61P31/00 ; C12Q1/48 ; G01N33/53
摘要:
Human PLK genes are identified as modulators of the beta catenin pathway, and thus are therapeutic targets for disorders associated with defective beta catenin function. Methods for identifying modulators of beta catenin, comprising screening for agents that modulate the activity of PLK are provided.
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