发明申请
US20080275098A1 NOVEL SUBSTITUTED 2-AMINOIMIDAZOLES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AID
审中-公开
新型取代的2-氨基嘧啶，其制备方法，用作药物或诊断辅助剂
- 专利标题： NOVEL SUBSTITUTED 2-AMINOIMIDAZOLES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENT OR DIAGNOSTIC AID
- 专利标题（中）： 新型取代的2-氨基嘧啶，其制备方法，用作药物或诊断辅助剂
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申请号： US12172380申请日： 2008-07-14
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公开(公告)号： US20080275098A1公开(公告)日： 2008-11-06
- 发明人: Uwe HEINELT , Hans-Jochen LANG , Armin HOFMEISTER , Klaus WIRTH , Hans-Willi JANSEN
- 申请人： Uwe HEINELT , Hans-Jochen LANG , Armin HOFMEISTER , Klaus WIRTH , Hans-Willi JANSEN
- 申请人地址： DE Frankfurt am Main
- 专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人： SANOFI-AVENTIS DEUTSCHLAND GMBH
- 当前专利权人地址： DE Frankfurt am Main
- 优先权： DE10304374.8 20030204
- 主分类号： C07D233/50
- IPC分类号： C07D233/50 ; A61K31/4168 ; C07D235/30 ; C07D317/72 ; A61P9/10 ; A61P3/00 ; A61P3/10 ; C07D317/10 ; A61K31/4184
摘要：
The present invention comprises novel substituted 2-aminoimidazoles of formula I, processes for their preparation, pharmaceutical compositions thereof, and methods for their use in the treatment of disorders of the central nervous system, cardiovascular disorders, stroke and pulmonary disorders, urinary disorders such as acute or chronic renal failure, disorders of biliary function, respiratory disorders such as snoring or sleep apnea. wherein the substitutents R1-R8 are further defined herein.
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