发明申请
- 专利标题： UREA ANTAGONISTS OF P2Y1 RECEPTOR USEFUL IN THE TREATMENT OF THROMBOTIC CONDITIONS
- 专利标题（中）： P2Y1受体的尿素拮抗剂用于治疗血栓病症
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申请号： US12117005申请日： 2008-05-08
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公开(公告)号： US20080280905A1公开(公告)日： 2008-11-13
- 发明人: Hannguang J. Chao , Huji Tuerdi , Timothy F. Herpin , Jaques Yves Roberge , Yalei Liu , R. Michael Lawrence , Robert P. Rehfuss , Charles G. Clark , Jennifer X. Qiao , Timur Gungor , Patrick Y. S. Lam , Tammy Wang , Rejean Ruel , Alexandre L'Heureux , Carl Thibeault , Gilles Bouthillier , Dora M. Schnur
- 申请人： Hannguang J. Chao , Huji Tuerdi , Timothy F. Herpin , Jaques Yves Roberge , Yalei Liu , R. Michael Lawrence , Robert P. Rehfuss , Charles G. Clark , Jennifer X. Qiao , Timur Gungor , Patrick Y. S. Lam , Tammy Wang , Rejean Ruel , Alexandre L'Heureux , Carl Thibeault , Gilles Bouthillier , Dora M. Schnur
- 申请人地址： US NJ Princeton
- 专利权人： Bristol Myers Squibb Company
- 当前专利权人： Bristol Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 主分类号： A61K31/5377
- IPC分类号： A61K31/5377 ; C07D213/72 ; C07D413/12 ; A61K31/4412 ; A61K31/4439 ; A61K31/4709 ; A61P7/00 ; A61P9/00 ; A61K31/4725 ; A61K31/444 ; A61K31/4545 ; A61K31/496 ; C07D401/12
摘要：
The present invention provides novel pyridyl or phenyl ureas and analogues thereof, which are selective inhibitors of the human P2Y1 receptor. The invention also provides for various pharmaceutical compositions of the same and methods for treating diseases responsive to modulation of P2Y1 receptor activity.