发明申请
- 专利标题: HIV vaccines based on Env of multiple clades of HIV
- 专利标题(中): 基于Env多个艾滋病毒携带者的艾滋病毒疫苗
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申请号: US11818113申请日: 2007-06-13
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公开(公告)号: US20080286306A1公开(公告)日: 2008-11-20
- 发明人: Gary J. Nabel , Bimal Chakrabarti , Wing-pui Kong , Yue Huang , Zhi-yong Yang , Zengguang Wang
- 申请人: Gary J. Nabel , Bimal Chakrabarti , Wing-pui Kong , Yue Huang , Zhi-yong Yang , Zengguang Wang
- 主分类号: A61K39/21
- IPC分类号: A61K39/21 ; A61P31/18
摘要:
In one embodiment, the invention provides a multiclade HIV plasmid DNA or viral vector vaccine including components from different clades of Env (optionally Env chimeras) and Gag-Pol-(optionally)Nef from a single clade. The vaccine of the invention may further include V1, V2, V3, or V4 deletions or combinations thereof. In another embodiment, the invention provides multiclade HIV envelope immunogens.
公开/授权文献
- US07666427B2 HIV vaccines based on Env of multiple clades of HIV 公开/授权日:2010-02-23