发明申请
- 专利标题: Solid Dispersion Comprising An Active Ingredient Having A Low Melting Point And Tablet For Oral Administration Comprising Same
- 专利标题(中): 具有低熔点的活性成分的固体分散体和包含其的口服给药片剂
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申请号: US12097299申请日: 2006-12-18
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公开(公告)号: US20080292702A1公开(公告)日: 2008-11-27
- 发明人: Jong Soo Woo , Sang Wook Kim , Hong Gi Yi , Jae Kuk Ryu
- 申请人: Jong Soo Woo , Sang Wook Kim , Hong Gi Yi , Jae Kuk Ryu
- 申请人地址: KR Hwaseong-gun, Kyungki-do
- 专利权人: Hanmi Pharm. Co. Ltd.
- 当前专利权人: Hanmi Pharm. Co. Ltd.
- 当前专利权人地址: KR Hwaseong-gun, Kyungki-do
- 优先权: KR10-2005-0124386 20051216
- 国际申请: PCT/KR2006/005526 WO 20061218
- 主分类号: A61K9/24
- IPC分类号: A61K9/24 ; A61K31/192 ; A61K47/38 ; A61K47/36 ; A61K47/02 ; A61K47/32 ; A61K9/22
摘要:
A fused solid dispersion comprising an active ingredient having a melting point of 800 C or below and a pharmaceutically acceptable absorbent having a specific surface area ranging from 20 to 400 mVg can be conveniently compressed into a tablet without generating capping and sticking problems, and a tablet comprising said fused solid dispersion can maintain an uniform release rate over a prolonged time when orally administered.
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