发明申请
- 专利标题: ANTIVIRAL DRUGS FOR TREATMENT OF ARENAVRUS INFECTION
- 专利标题(中): 用于治疗ARENAVRUS感染的抗病毒药物
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申请号: US12111778申请日: 2008-04-29
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公开(公告)号: US20080300265A1公开(公告)日: 2008-12-04
- 发明人: Dennis E. Hruby , Tove C. Bolken , Sean Amberg , Dongcheng Dai , Ryan A. Larson
- 申请人: Dennis E. Hruby , Tove C. Bolken , Sean Amberg , Dongcheng Dai , Ryan A. Larson
- 申请人地址: US NY New York
- 专利权人: SIGA TECHNOLOGIES INC.
- 当前专利权人: SIGA TECHNOLOGIES INC.
- 当前专利权人地址: US NY New York
- 主分类号: A61K31/513
- IPC分类号: A61K31/513 ; A61K31/4184 ; A61P31/12
摘要:
Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain novel compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by hemorrhagic fever viruses is disclosed, i.e., including but not limited to, Arenaviridae (Junin, Machupo, Guanarito, Sabia, Lassa, Tacaribe, Pichinde, and LCMV), Filoviridae (Ebola and Marburg viruses), Flaviviridae (yellow fever, Omsk hemorrhagic fever and Kyasanur Forest disease viruses), and Bunyaviridae (Rift Valley fever and Crimean-Congo hemorrhagic fever).
公开/授权文献
- US07977365B2 Antiviral drugs for treatment of arenavirus infection 公开/授权日:2011-07-12
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