发明申请
- 专利标题: Mutant Porcine Reproductive and Respiratory Syndrome Virus
- 专利标题(中): 突变型猪繁殖与呼吸综合征病毒
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申请号: US11718828申请日: 2005-11-02
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公开(公告)号: US20090004221A1公开(公告)日: 2009-01-01
- 发明人: Dongwan Yoo , Changhee Lee , Jay Gregory Calvert
- 申请人: Dongwan Yoo , Changhee Lee , Jay Gregory Calvert
- 申请人地址: US CT Groton
- 专利权人: PFIZER PRODUCTS INC.
- 当前专利权人: PFIZER PRODUCTS INC.
- 当前专利权人地址: US CT Groton
- 国际申请: PCT/IB05/03366 WO 20051102
- 主分类号: A61K39/12
- IPC分类号: A61K39/12 ; A61K35/76 ; C12N5/10 ; C12N15/09
摘要:
The present invention provides a genetically modified PRRS virus which has been modified such that the conserved cysteine in the E protein has been deleted or changed to a non-cysteine residue and polynucleotides that encode it. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
公开/授权文献
- US07879337B2 Mutant porcine reproductive and respiratory syndrome virus 公开/授权日:2011-02-01
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