Invention Application
US20090017066A1 NOVEL VLPS DERIVED FROM CELLS THAT DO NOT EXPRESS A VIRAL MATRIX OR CORE PROTEIN
有权
从不能表达病毒基质或核心蛋白质的细胞衍生的新型VLPS
- Patent Title: NOVEL VLPS DERIVED FROM CELLS THAT DO NOT EXPRESS A VIRAL MATRIX OR CORE PROTEIN
- Patent Title (中): 从不能表达病毒基质或核心蛋白质的细胞衍生的新型VLPS
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Application No.: US12127625Application Date: 2008-05-27
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Publication No.: US20090017066A1Publication Date: 2009-01-15
- Inventor: Gale Smith , Peter Pushko , Kutub Mahmood , Bin Zhao
- Applicant: Gale Smith , Peter Pushko , Kutub Mahmood , Bin Zhao
- Main IPC: A61K39/145
- IPC: A61K39/145 ; C07K14/11 ; A61P31/16 ; C12P21/02
Abstract:
The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.
Public/Granted literature
- US08697088B2 VLPs derived from cells that do not express a viral matrix or core protein Public/Granted day:2014-04-15
Information query
