发明申请
- 专利标题： PARTICLE AND PREPARATION CONTAINING THE PARTICLE
- 专利标题（中）： 颗粒和包含颗粒的制备
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申请号： US11908091申请日： 2006-03-08
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公开(公告)号： US20090022915A1公开(公告)日： 2009-01-22
- 发明人: Hideo Masuda , Hikaru Sugihara , Akio Nishiura , Kazuyuki Hayashi
- 申请人： Hideo Masuda , Hikaru Sugihara , Akio Nishiura , Kazuyuki Hayashi
- 申请人地址： JP Osaka-shi
- 专利权人： ONO PHARMACEUTICAL CO., LTD.,
- 当前专利权人： ONO PHARMACEUTICAL CO., LTD.,
- 当前专利权人地址： JP Osaka-shi
- 优先权： JP2005-066158 20050309
- 国际申请： PCT/JP2006/304506 WO 20060308
- 主分类号： C07D417/02
- IPC分类号： C07D417/02 ; B32B1/02 ; B32B5/16
摘要：
The present invention relates to a particle having a mean particle size of 0.01 to 20 μm, containing tert-butyl (4R)-4-{[((1R)-2-[(1-benzylpiperidin-4-yl)amino]-1-{[(cyclohexylmethyl)thio]methyl}-2-oxoethyl)amino]carbonyl}-1,3-thiazolidine-3-carboxylate. A preparation containing the particle is excellent in pulmonary delivery through inhalation and is easy to handle because of excellent dispersibility of the particle, and thus the present compound can be used as a pulmonary preparation.
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