Invention Application
US20090025095A1 Method for Evaluating Compound Using Barlp and Substance for Regulating Eating and Body Weight
审中-公开
使用Barlp和物质评价化合物调节饮食和体重的方法
- Patent Title: Method for Evaluating Compound Using Barlp and Substance for Regulating Eating and Body Weight
- Patent Title (中): 使用Barlp和物质评价化合物调节饮食和体重的方法
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Application No.: US11918099Application Date: 2006-04-25
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Publication No.: US20090025095A1Publication Date: 2009-01-22
- Inventor: Hirohide Nambu , Satoshi Ozaki , Takeshi Tanaka , Hisashi Ohta
- Applicant: Hirohide Nambu , Satoshi Ozaki , Takeshi Tanaka , Hisashi Ohta
- Priority: JP2005-127772 20050426
- International Application: PCT/JP2006/309122 WO 20060425
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N33/00 ; C07K16/00 ; C07H21/04 ; C07H21/02 ; C07K14/00 ; C07K2/00
Abstract:
It is intended to provide a method for evaluating a compound which regulates eating or body weight characterized by comprising the steps of introducing a BARLP gene and preparing a cell expressing BARLP; bringing a test compound into contact with the cell; and detecting a specific binding of the test compound to the BARLP and a method for evaluating a compound further comprising the step of evaluating a test compound using a nonhuman genetically-engineered animal in which the BARLP gene is inactivated. According to this invention, knowledge about a relationship between BARLP and biological functions is obtained and a method for evaluating a compound targeting BARLP and a BARLP ligand obtained by the evaluation can be provided.
Information query
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