发明申请
US20090036422A1 MONOAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS 审中-公开
单酰胺衍生物作为OREXIN受体拮抗剂

MONOAMIDE DERIVATIVES AS OREXIN RECEPTOR ANTAGONISTS
摘要:
The present invention relates to compounds of formula wherein Ar, R1, R2, R3, R4, R5, n, o, and p are as defined herein or to pharmaceutically suitable acid addition salts, optically pure enantiomers, racemates or diastereomeric mixtures thereof. The compounds of formula I can be used for the treatment of sleep disorders, such as sleep apnea, narcolepsy, insomnia, parasomnia, jet lag syndrome, circadian rhythms disorder or sleep disorders associated with neurological diseases.
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