发明申请
- 专利标题： SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES
- 专利标题（中）： 取代的双环吡啶酮衍生物
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申请号： US12122111申请日： 2008-05-16
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公开(公告)号： US20090036427A1公开(公告)日： 2009-02-05
- 发明人: Nathalie CHEREZE , Alistair LOCHEAD , Mourad SAADY , Franck SLOWINSKI , Philippe YAICHE
- 申请人： Nathalie CHEREZE , Alistair LOCHEAD , Mourad SAADY , Franck SLOWINSKI , Philippe YAICHE
- 申请人地址： FR Paris JP OSAKA
- 专利权人： SANOFI-AVENTIS,MITSUBISHI TANABE PHARMA CORPORATION
- 当前专利权人： SANOFI-AVENTIS,MITSUBISHI TANABE PHARMA CORPORATION
- 当前专利权人地址： FR Paris JP OSAKA
- 优先权： EP05292457.8 20051121
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61K31/519 ; C07D487/04 ; A61P25/28 ; A61P25/16 ; C07D471/04
摘要：
A pyrimidone derivative represented by formula (I) or a salt thereof, or a solvate thereof or a hydrate thereof: Wherein Y, Z, R1, R2, R3, R4, R5, R6, R7, n, m, and o are as described herein. The invention relates also to a medicament comprising the said derivative or a salt thereof as an active ingredient which is used for preventive and/or therapeutic treatment of a neurodegenerative disease caused by abnormal activity of GSK3β, such as Alzheimer disease.
公开/授权文献
- US08148364B2 Substituted bicyclic pyrimidone derivatives 公开/授权日：2012-04-03
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