Disclosed are an insulated container in which a high-performance vacuum heat insulating material is formed around a three-dimensional container and in which heat loss is minimized, and a method of manufacturing the insulated container. An insulated container for heat-insulation storage of a liquid has a resin inner container equipped with liquid flow inlet/outlet portions, an interior member and an exterior member which accommodate the inner container and around which a gas barrier layer is formed, and a heat insulation space which is defined between the interior member and the exterior member and which is held in a pressure-reduced state, with a heat insulating material being sealed therein. Further, flange members are fitted onto the flow inlet/outlet portions, lower flange surfaces of the flange members are bonded to the interior member, and upper flange surfaces thereof are bonded to the exterior member.