A lithium ion secondary battery includes a negative electrode that is shaped like waves in a section in the thickness direction. In the negative electrode, the ratio t1/t0 of the largest thickness t1 to the smallest thickness t0 is from 1.2 to 3.0. The negative electrode includes a thin-film negative electrode active material layer in which the ratio A/B of the volume A in a charged state to the volume B in a discharged state is 1.2 or more. The lithium ion secondary battery has high capacity, high power, long life, and improved safety. In particular, heat generation due to an internal short-circuit is significantly suppressed in a nail penetration test.