发明申请
US20090042250A1 Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
有权
用于灭活α16岩藻糖基转移酶（FUT8）基因表达的方法和组合物
- 专利标题： Methods and compositions for inactivating alpha 1,6 fucosyltransferase (FUT8) gene expression
- 专利标题（中）： 用于灭活α16岩藻糖基转移酶（FUT8）基因表达的方法和组合物
-
申请号： US12218035申请日： 2008-07-10
-
公开(公告)号： US20090042250A1公开(公告)日： 2009-02-12
- 发明人: Trevor Collingwood , Gregory J. Cost
- 申请人： Trevor Collingwood , Gregory J. Cost
- 专利权人： Sangamo BioSciences, Inc.
- 当前专利权人： Sangamo BioSciences, Inc.
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; C07K14/00 ; C07H21/02 ; C07H5/10 ; C12N5/06 ; C12N15/87
摘要：
Disclosed herein are methods and compositions for inactivating a FUT8 gene, using fusion proteins comprising a zinc finger protein and a cleavage domain or cleavage half-domain. Polynucleotides encoding said fusion proteins are also provided, as are cells comprising said polynucleotides and fusion proteins.
公开/授权文献
信息查询
